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I see where you're going here, but I see too much self-discard. While this won't hurt you via the Megrim or Caress, it will hurt ensuring that you have threats in your hand to continue the damage to your opponent. With that said, you might want to consider going the mono-black route as it will cater to your desires much better. Look towards cards like Duress, Hymn of Tourach, or Thoughtseize; Inquisition of Kozliek and Blackmail are also solid choices. Ideally, you want to have a a number of turn 1 threats so that you can disrupt their hand/strategy as soon as possible. I like the addition of Damnation here, if you have a few more, I'd strongly suggest running at least three in the event you need to stall; Diabolic Edict/Chainer's Edict or Doom Blade/Go For the Throat are all viable options for removal in place of Terminate. In terms of a creature base, look towards old classics like Hypnotic Specter to get you in for quick damage and discard. For protection, Will-o-the-Wisps might serve useful. Nyathid is a great play here, of course, I'd run at least 2 of those and compliment them with Demonic Tutor. Liliana Vess would be a great replacement for Chandra, too, if you would like to maintain the presence of a planeswalker (her third loyalty ability could mean a lot of good things for you, and she'll give you a free discard every turn). I hope these suggestions don't steer away from what you'd ultimately like to do with this build. You have the foundations for some solid things to happen. If you get the chance, I welcome any comments or suggestions you could offer any of the decks I have posted here. Thanks!
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this deck is just with cards i have so unfortunately i cannot use hymn of torach. i like your ideas but i think that i want to maintain red. i tend to drop the self discard cards when i only have the one card in my hand to use it. i wish i had more damnations i only got the one in a pack and i dont want to spend 15 bucks just for one card : /. the card that hurts me the most is burning inquiry but i tend to use that later in the game. its a one mana 6 dmg drop so it helps alot. also if they have no cards in there hand it helps to do damage.
since you are using mind twist... remove mind rot and put hym to tourach